ISSN 1662-4009 (online)

ey0019.4-4 | Important for clinical practice | ESPEYB19

4.4. Effects of growth hormone treatment on sleep-related parameters in adults with Prader-Willi syndrome

HH Shukur , L Hussain-Alkhateeb , Farholt S , O Norregaard , AP Jorgensen , C Hoybye

The Journal of Clinical Endocrinology & Metabolism, 2021, Vol. 106, No. 9, e3634–e3643PMID: 33950234Brief Summary: This trial explored the effects of rhGH treatment in patients with Prader-Willi syndrome (PWS) on respiratory and sleep parameters. The trial was randomized and placebo-controlled for 1 year, followed by a 2-year, open-phase GH treatment period. Polysomnography performed every 6 months revealed no adverse effects of rhGH tr...